The authors (HDR, JAJ) have previously reported on the use of high dose intravenous vitamin C in the treatment of patients with various types of cancer.^1-4 Research conducted at The Center has also been published to help explain the scientific basis for the dynamics of intra venous vitamin C.^5-7 Many health care workers are wary of giving high dose vitamin C to patients due to the warning that “one could develop kidney stones with high dose vitamin C.” The possibility of kidney stones does exist, theoretically, because vitamin C (ascorbic acid) is water soluble and is excreted by the kidneys as oxalic acid. Since most kidney stones consist of some form of oxalate, it would seem to follow, to some people, there must be kidney stones. In reality, this never happens. Another question comes to mind, why are there thousands of people with kidney stones who DO NOT take large doses of vitamin C?