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The Journal of Orthomolecular Medicine Vol. 13, 4th Quarter 1998

ABSTRACT

The Application of the Hardin Jones-Pauling Biostatistical Theory of Survival Analysis for Cancer Patients to a Clinical Trial Purporting to Test the Efficacy of Vitamin C in Lengthening the Survival Times of Patients with Advanced Colorectal Cancer

Z.S. HERMAN, Ph.D.

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The Hardin Jones-Pauling biostatistical theory of survival analysis for cancer patients leads naturally to three criteria/or the validity of clinical trials of treatments for charts of cancer patients. These three criteria are presented.

The well-publicized Mayo Clinic study claiming the lack of efficacy of vitamin C in prolonging the lives of patients with advanced colorectal cancer is shown to violate each of the three criteria. A detailed account is given of the reprehensible treatment received by Linus Pauling and the author/rom the New England Journal of Medicine when they attempted to publish ïheir analysis of the Mayo Clinic study in The New England Journal of Medicine.


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