It is well known by many clinicians in the field of complementary and alternative medicine that vitamin B3 has numerous therapeutic indications. The many review articles, case reports, and books authored by Hoffer fully elucidate the known and theoretical benefits of vitamin B3 administration for the treatment of AIDS, alcoholism, arthritis, cancer, cardiovascular disease, childhood learning and behavioral disorders, longevity, post-traumatic stress disorder, schizophrenia and senility. Despite the breadth of Hoffer¹s work, there has been no direct description regarding the usefulness of vitamin B3 for the treatment of hypochlorhydria and achlorhydria conditions denoting a lack and absence of stomach (gastric) acid secretion.