Leonard John Hoffer, MD, PhD
Hall of Fame 2015
Leonard John Hoffer is a Professor of Medicine at McGill University and Associate Professor in McGill’s School of Dietetics and Human Nutrition. He is a full-time investigator in the Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, and a Senior Physician in the Divisions of General Internal Medicine and Endocrinology in the JGH, where he serves on the nutritional support team.
Dr. Hoffer obtained his medical and subspecialty training in internal medicine at McGill, then a PhD in Human Nutrition at the Massachusetts Institute of Technology, Cambridge MA, a clinical fellowship in nutritional support at Harvard Medical School, and a post-doctoral fellowship in biochemistry at Brandeis University, returning to McGill in 1984 as an assistant professor. Dr. Hoffer’s research and clinical interests focus on the relationship between disease and malnutrition, the metabolic adaptation to starvation, and micronutrient metabolism in disease. He authored the chapter on the metabolic features of human starvation in the last several editions of the clinical nutrition textbook, Modern Nutrition in Health and Disease, and co-authored the chapter entitled "Enteral and parenteral nutrition therapy" in the 2015 edition of Harrison’s Principles of Internal Medicine, the world’s most prestigious medical textbook. In 2012 he was recipient of the Kursheed Jeejeebhoy Award and Plenary Lecture, Canadian Nutrition Society.
Influenced throughout his career by the ideas of his father, Abram, John Hoffer has spent much of his career thinking about and studying the therapeutic potential of nutrition in the treatment of important diseases, including cancer. He has served on the editorial board of the Journal of Orthomolecular Medicine for decades, and since 2009 as associate editor. With funding from the Hecht Foundation, he was able to contribute to interest in and study of the use of high-dose vitamin C in cancer therapy.